Power and Energy Systems will play a crucial role in the 21st century as major driver of economic growth and sustainable development. This Panel will discuss the most promising technologies to invest in the next future with a medium term view. Governments can promote the electrification of end-uses in all sectors with benefits on climate (energy efficiency and de-carbonization). Electricity will establish itself as the global leading energy source by 2050 increasing shares in buildings, transportation and industry. The panelists will discuss innovation opportunities and technology trends which will be able to enlarge the current domain of efficient electric systems, bridging the gap between research and markets, potentially providing great return on investments and new companies. As outcome of the Plenary 1 we expect a future strategic roadmap reckon with the context of R&D, venture capital, corporate finance, EU regulation and policy issues.